Dangers of Using Accutane

One of the most effective acne treatments for patients who suffer from severe acne scarring is Isotretinoin AKA Accutane. In general, it takes 4 to 5 months for the medication to eliminate cases of acne severe enough to warrant the use of Accutane after all other treatment options have failed. It is also useful in treating acne that has not shown a complete response to creams or antibiotics. Accutane was approved by the FDA in 1982 for use as an acne medication. The American Academy of Dermatology has reported that 85% of patients who use Accutane have results that range from long-lasting to a complete reduction of acne.

Accutane Dangers

How It Works

Accutane belongs to the retinoid medication class which includes drugs that are used in cancer treatments. In fact, the drug was originally marketed as a chemotherapy drug. Accutane works by controlling the oil located in the sebaceous gland and is most often used to treat acne with nodules that are 5-mm or larger in diameter. The dosage of Accutane taken by a patient depends on his or her body weight. As mentioned above, it can take up to 4 or 5 months for the treatment to eliminate the acne.

Side Effects

As effective as Accutane is for treating severe acne, it is also known to cause side effects that range from mild to severe.

Some of the milder, and most common, side effects include:

  • Nosebleeds
  • Dry eyes
  • Cracked/Peeling skin
  • Pain in the back, joints and muscles
  • Fatigue
  • Headaches
  • Dizziness
  • Swollen or Bleeding gums

There are also a number of serious side effects associated with Accutane and they include:

  • Psychiatric disorders such as depression, aggressive behavior and suicidal thoughts
  • Inflamed bowels
  • Pancreas inflammation
  • Pseudotumor cerebri (a buildup of pressure in the skull that mimics a brain tumor)
  • Bone loss

Birth Defects

Accutane has been known to cause birth defects in women. As far back as 1985, the FDA added a black box warning telling pregnant women (or women who hope to become pregnant) not to use Accutane because of possible birth defects including fetal deformities and potential fetal death. These potential birth defects can happen even if Accutane is only taken for a short period of time by a woman who is pregnant. Some of the serious birth defects that can occur include:

  • Eye and ear abnormalities
  • Cleft palate
  • Problems with the heart and brain
  • Facial dysmorphia
  • Central nervous system malformations
  • Fetus death

Interactions with Other Drugs

Anyone who uses Accutane should be aware of how it interacts with other drugs. Patients need to consult with a board-certified physician before making the decision to actively use Accutane. While the label on the medication informs patients of the lengthy list of interactions, here are some of the most common interactions associated with Accutane:

  • Vitamin A – Toxicity can be the result if used with Accutane
  • John’s Wort – Taking this product while also using Accutane can decrease birth control effectiveness and lead to pregnancy
  • Tetracycline – When combined with Accutane, the risk of pseudotumor cerebri increases
  • Phenytoin – Since this drug can cause low mineral density in bones and Accutane can cause bone loss, the two should not be taken at the same time

New Science Helps in Healing Victims of War

Traumatic Injures of War

A young child in Mosul, Iraq is playing in a war torn neighborhood. Chasing a ball made of newspaper in tape she inadvertently steps on an IED. Outside Kabul a coalition humanitarian worker and a soldier a bring aid to an Afghan family. There vehicle hits a landmine they are severely burned and scarred from burns and loss of muscle. New technology promise hope for such victims.

University of Pittsburgh doctors have helped a soldier injured in Afghanistan regrow muscle to restore his strength and range of motion in his severely injured leg. McGowan Institute for Regenerative Medicine, at the University of Pittsburgh is headed by Stephen Badylak, doctors there are pioneering cutting edged treatments for recovery of traumatic battlefield wounds. These injuries include burns and blast injuries. These amazing treatments include wound healing, craniofacial reconstruction, and limb regeneration.

Wounded Soldier Facial Reconstruction

“Wounded Soldier Facial Reconstruction -Midway through surgical series.”

A new therapy developed at the institute is called the “skin gun.” It is actually a spraying device used to spray wounded areas with skin cells over burns on the ears and face. Skin can regrow over the affected burn areas in just a matter of days. The Bioreactor Group is under the direction of Professor Joerg Gerlach, they are the developers of this exciting restorative treatment.

There are three innovative treatment programs headed by the McGowan medical team. Extensive research on biominerlization (scaffolding) and bioceramic nanoparticles in non-viral DNA gene delivery. Professor Charles Sefeir leads the studies focused on the role of extracellular matrix in tissue engineering and biominerliazation.

One of the most critical areas of the centers work is the reconstruction of soldiers’ faces with the most normal looking appearance as possible for the patients. A cross functional team led by Professor J. Peter Rubin coordinate their complimentary expertise to bring about positive results with the advancement medical treatments of the McGowan Institute.

A Scars Story

Scar Truths and Tales

Scars, who doesn’t have one? A little annoying insect bite gets scratched obsessively becomes infected and though not deep it scars. The athletic endeavors of youth, life threatening accidents, surgery or to the catastrophic injuries of war can all leave our bodies scared. Scars can be the source of pride for some an icebreaker to tell an embellished tale at a family event or hob-knobbing with friends.

Scars can just be minor footnotes to our lives or major source of emotional and psychological angst. One on my right palm once stretched the full width; now, it is barely noticeable unless pointed out. It marks a dramatic bloody incident of falling in a 2nd grade foot race at recess. Then there is the one near my right eye a story that I don’t often want to recount. The visible one on my right shoulder blade always invites comment in a shirtless pickup game of basketball. Scars can be mileage markers on the amazing journey of our life. Sometimes, those scars bare even more tragic consequences to some people. They can infringe upon their well-being and devastate their quality of life.

View Amazing Scar Revision Surgery on Young Girl

The more I reflect my hands begin to braille my body through my clothing and my mind shuffles through vignettes of memories of burns and bruises, scrapes and scabs; bumps and lumps. Limbs and torso marked by stitches and scratches, gashes and slashes; all with the requisite blood; some of these scars bleeding more profusely causing parental angst and a flood of tears.
My active childhood, athletics and sporting lifestyle have given my dermis a lifetime of stories and embellished tales to share. Not a one would I remove. They are my story for better and worse.

By now you’re asking the purpose of this tale. My many scars have left to date only memories to be romanced and morphed into heroic tales. This is not true for many people. Scarring can deeply mar the psyche of a person and impact their life at every level.

Scar revision provides an opportunity to effect positive change on such people’s self image and esteem. The effect of scarring can be compounded by the onset of depression; a too often debilitating life-cycle if untreated.

It can be a vitally important step in their journey to inner and outer healing to treat the scar through the wonderful advancements in scar revision treatment. If you or a family member or friend struggle with issues regarding scars; consult with a dermatologist and or cosmetic surgeon. Scar revision in the 21st century has come a long way in providing wonderful results for many.

Preventing Scars

Preventing Scars

Whether it’s a child bumping his head on the edge of a table or an adult slipping with a kitchen knife while cutting up vegetables, accidents happen no matter how careful you are being. Injuries and scars often- abound. After a cut it is impossible to not have a scar, but there are things you can do to lessen the severity of any lasting marks. Some scars are called sexy at times but for the most part people don’t like scarring.

Scar Prevention: Do’s and Don’ts

To help heal the skin with as little residual scarring as possible, there are steps you may take, and mistakes to avoid. “The key to lessening scarring is to decrease the amount of work the body has to do to heal the scar,” Krant says. Here’s how:

  • Stitches can be used if needed. Often times when you have a cut that is spread apart or deep its always better to have them stitched by a medical professional. Always keep in mind that when the wound or injury is fresh, stitches must be sewn as soon as possible. If you let too much time pass by since the injury, the wound can become contaminated with bacteria, germs, and the doctor will not want to stitch it closed because of the risk of infection. But the wound may start to heal, which can obstruct successful suturing. When having doubts if whether stitches are in order, contact a doctor in a timely manner and let him decide the best treatment for the wound.
  • Applying petroleum jelly to the wound and covering it with a non-stick bandage, and alsokeeping the wound moist, can speed up the healing and minimize scarring, says Krant.
  • Scar Creams and Ointments – There will always be advertisement for scar creams, don’t fall for them. You may have herd that vitamin E can help with reducing the scarring, but this actually has been proven in high-quality studies (a double-blind, placebo-controlled trail). As a matter of fact, there is no over-the-counter product claiming to prevent scars that has been scientifically shown to significantly improve scarring.
  • Massage the wound – Krant claims, that by massaging the scar daily with vitamin E may help promote a less visible scar.
  • Avoid the sun – By keeping the scar away from sunlight it can help minimize discoloration.
  • Let it heal naturally – When using hydrogen peroxide constantly on a wound it would cause irritation and slow down the healing process. Krant says “Scabs are nature’s biologic dressing, Picking off a scab repeatedly when a wound is trying to heal will slow healing and increase scarring.” So it would be best to not pick on scabs.
  • Healing takes time, perhaps a long time. So be patient. The first stage of healing takes three months, followed by the second stage that lasts another three months. One year after the injury the injury has already been formed, but the scar still may change in the following year. “The truth is, that scars never stop changing and improving unless they are keloid scars, which continually worsen unless treated by a physician,” says Krant.

Types of Surgical Scar Revision


Description of Types of Surgical Scar Revision


Listed below are the most common surgical techniques utilized in scar revision.
Z-plasty Before & After

Z-plasty is a reconstructive surgery procedure. Its utilization is for improving the functional and aesthetics of scars.  Functionally refers to the lengthening of the scar the lengthening of a scar which helps relax or release linear burn scar contractures. The availability of mobile adjacent skin is a predicator for the use of this medical procedure. Z-plasty can procedurally make the scar less noticeable. Re-alignment of the central element can place the scar in natural skin tension lines and thereby disguise it. Utilizing this procedure the surgeon can rotate the tension line of a scar and or make a contracted scar elongated. In Z-plasty the midline of the Z-shaped incision is made along the meridian of highest tension or contracture. Triangular flaps are raised on the opposite ends of this incision. The flaps are than transposed and closed.

W-plasty is another reconstructive plastic surgery technique used for the excision of unaesthetic scarring. The excised edges of the scar are cut in a zig-zag pattern is like a connected row W’s. The borders are interdigitated for suturing. This method is very effective in rendering a linear scar irregular and less visible.

W-plasty Diagram

W-plasty revisions the scar into a ‘pinking shear pattern; which will interlock when sutured. Optically, it is more difficult for the eye to follow an irregular line. This makes W-plasty a favored method for revisioning linear scars. Often there is no discreet skinfold to hide a scar. Think of areas such as the forehead, the side of the face or cheek. Still is the irregular pattern is uniform visibility is not obscured. For that reason W-plasty is most often combined with

Geometric Broken Line Closure (GBLC).

W-plasties are not usually employed on their own throughout the entire scar. Visibility of the scar can be better reduced by combining other patterns with the W pattern. This is a more sophisticated procedural technique of scar revision is known as geometric broken line closure (GBLC).  W-plasty is the basic technique and then other shapes besides triangular flaps are utilized for interdigitation creating a very irregular irregularity. This procedure offers the optimal potential for camouflaging the scar. Added to this is also dermabrasion which is done approximately two to three months after the surgery.

M-plasty

The object of electing M-plasty in reconstructive surgery is to better preserve healthy tissue and to reduce the chance of secondary tissue deformity.  Proper technique in M-plasty reduces the loss of surrounding health tissue by nearly fifty percent.  The M-plasty is performed by creating two separate thirty degree angles instead of a single one.

 
 

Adjunctive Techniques of Scar Revision

 

Dermabrasion

  • precisely and in a controlled deliberate manner superficial abrading of the scar and surrounding skin. The end result is a smooth texture and in some cases further reduced visibility.
  • Abrasion can be used in a process that will improve the appearance of uneven scar edges including: scar edges, grafts and or flaps.
  • Dermabrasion works best on lighter complexions because of the lower risk of dyspigmentation.

Intralesional Steroids

  • Hypertrophic linear scars, bulky grafts and flaps, can be treated with intralesional corticosteroids. Injections can be instituted at approximately 1 month postoperatively.
  • A small amount (as little as 0.1 mL) of low-dose triamcinolone acetonide  at 5 to 10 mg/mL is injected into the scar; this dosage can be repeated monthly until the scar has flattened.
  • Side effects include atrophy (if the injection leaks out into healthy skin ),  hypopigmentation and telangiectasias when injected in higher concentrations into the dermis.

Contraindications

The reasons for a patient not to undergo scar revision include:

  1. The present psychological status of the patient does not prepare the patient for a positive outcome.
  2. The patient’s expectations are unrealistic limiting the opportunity for a favorable visible outcome.
  3. An individual’s history for hypertrophic and or keloid scarring represent a poor risk for a pleasing aesthetic result.
  4. Patient’s with thickened skin from the trauma reducing compliancy endure the risk of a compromised scar revision.

Scar Revisions New Horizons with Lasers

Laser Instrumentation for DermatogistsScars are immensely varied and come in all shapes and sizes. Surgery remains the best option for more severe scars, other scars can be treated with the advance development of lasers for dermatological use. Treatment of scars with laser has steadily grown, giving both patients and physicians more flexibility to determine the best method of treatment.

Two Main Goals of Treatment
Scars appear different, depending on the injury sustained. According to some experts the color be it, white, red, or brown, can be an indicator of the type of texture the scar will show.
• Make the scar smooth without the is not depressed or elevated
• Blend the color around and within the scar so that it blends with the outlying pigment

Ablative Technology

For larger and more severe scars, such as burns and contractions associated with scars, ablative technology is a better option. Ablative technology is a process of placing tiny holes in the skin with lasers that allow tissue to bend more easily, thus potentially increasing the range of motion in severe scars. This technology continues to improve through the enabling deeper penetration of the lasers.
With lasers now offering the ability to go deeper into the skin scar treatment will continue its dramatic changes.

Some dermatologists and researchers theorize that deeper treatments will allow for more range of motion in scars that restrict movement; this may open up whole new possibilities for scar treatments. Lasers in the future will allow for even deeper penetration of the dermal layers.

Given the nature of scars, there will likely never be a definitive treatment for all scars, no matter how much the technology advances. Still the current levels of laser therapy provide wonderful new treatments to diminish scarring; with greater promise on the future.

Innovative Treatment for Scalp Scar Revision

Follicular Unit Extraction (FUE)

Innovative Treatment for Scalp Scar RevisionFUE for Scar Revision

Follicular units (FUs) are the individual removal of the tiny organs that produce our hair shafts. Hair loss is a growing elective surgery but very beneficial for people who are suffering from low self image and quality of life issues from hair loss.

Like all surgeries hair transplants leave a scar. Dr. Parsa Mohebi, medical director of US Hair Restoration center is pioneering method of combining two procedures to render these scars virtually undetectable in many cases. The combination of FUE and SMP are small procedures that can be used in the revisioning of a hair transplant scar.

Donor Hair Scar Revised

The surgeon can extract a small number of grafts from the permanent zone and artistically and strategically place them in the scar. This process of using FUE uses hair to obscure and blend the margins of the scar to the surrounding scalp. Scalp Micro-pigmentation (SMP) can be used to further blend the scar in many cases.

Scalp Micro-Pigmentation

SMP for Scar Revision

Scalp Micro-Pigmentation is the process of using special pigments and fine needles to create the shade of stubble or shaved hairs on the scalp. SMP utilizes dermal pigments that match the patient’s hair color. Used in scars like FUE it can artistically applied revises the margins of the scars. This revision results in the obscuring or blending of the scars margins to the surrounding scalp.

FUE and SMP

FUE and SMP are a very non invasive way of revisioning a hair transplant scar. Patients can consult a hair transplant surgeon for recommendations on achieving the best results. These modern advances in scalp scar revision are performed in Los Angeles leading hair transplant centers like US Hair Restoration.

Abdominal Scars

Abdominal Surgical Revision

Abdominal scar tissue is forms through the healing of the connective fibers surrounding incision sites or traumatic wound. These are the natural fibers the body creates to heal tears in the skin. Abdominal scar removal is a way to repair or replace damaged skin. The severity of the wound surgical or traumatic helps determine the realistic level of success of any abdominal scar removal technique or revision.

Surgical Revision

Surgical scar revision is often used to reduce the abdominal scar. Surgical revisions work by moving the scar toward a natural crease in the skin. Scarring is ofthen cause by too much tension on the wound. In an abdominal surgical scar revision a less prominent scar will result because of he conrol of the woud tension which is lessend by the surgeons expertise.

View an actual abdominal scar revision with dermabrasion.

Punch Graft Scar Revision

A punch graft is a surgical technique designed to minimize the appearance of a scar. By removing an area of tissue from another area (normally less visible area of the body) and replacing it where the scar was located. If the abdominal scar is severe, a punch graft may be used and the skin is placed over the abdomen and stitched in place. Again, the tension in the stitching or closure of the surgical wound lends to a more aesthetic or less obvious scar. In addition after full healing of the punch graft dermabrasion or laser resurfacing can be utilized to diminish the appearance of scars.

Considering Scar Revision Surgery

Enhancing your appearance with scar revision surgery

There is not a person on the planet who is scarless or a tleast it is highly unlikely. Scars are visible signs that remain after a wound has healed. Scars are unavoidable results of injury or surgery, and the results of this natural healing process can be very unpredictable. Some people naturally heal well; others do not… Poor healing may contribute to scars that are unsightly or disfiguring. Even a wound that heals well can result in a scar that affects your appearance. Scars may be raised or recessed, different in color or texture from surrounding healthy tissue or particularly noticeable due to their size, shape or location.

Facial Scar on Young GirlYour treatment options vary based on the type and degree of scarring and can include:
• Simple topical treatments
• Minimally invasive procedures
• Surgical revision with advanced techniques in wound closure

Scar revision surgery is meant to minimize the scar so that it is more consistent with your surrounding skin tone and texture.
Although scar revision can provide a more pleasing cosmetic result or improve a scar that has healed poorly, a scar cannot be completely erased.

Should I Elect Scar Revision?

Scar revision is a highly individualized procedure and you should do it if it adversely effects your self image and esteem.. Scar revision can be performed at any age and is a good option if:

• You are upset by a scar anywhere on your body
• You are physically healthy
• You do not smoke
• You have a positive outlook and realistic goals for your scar revision surgery
• You do not have active acne or other skin diseases in the area to be treated

Healing the Scars of War Victims

No single group deals with more debilitating scarring then victims of war; both military and civilians. The decade of wars heralding in the 21st Century has left millions of people suffering from life changing injures. Along with the emotional and tragic psychological scars are the physical scars as a reminder. There are organizations globally seeking to help people who unfortunately suffering from the life lone effects of debilitating human conflict. Share this resource with any person who can benefit.

Thanks the MEDSCAR team.

AFIRM
The Armed Forces Institute of Regenerative Medicine (AFIRM) is a multi-institutional, interdisciplinary network working to develop advanced treatment options for our severely wounded servicemen and women. They develop advanced treatment for severely wounded servicemen and women. This organization is designed to speed the delivery of regenerative medicine therapies to assist the most injured service members. The five major research programs include Burn Repair, Compartment Syndrome Repair, craniofacial Reconstruction, Limb and Digit Salvage, and Scarless Wound Healing.

Air Force Wounded Warrior
The Air Force Wounded Warrior ensures great care, services, and assistance before and after wounded warriors separate or retire. They have a strong emphasis on ensuring wounded airmen individualized guidance and support to help them transition out of the Air Force and back to civilian life. The Air Force Wounded Warrior, working closely with the Secretary of Defense programs, will keep these men and women on active duty.

Iraq Star, Inc.
Iraq Star is a recently founded non-profit organization. It offers surgery for disfigured veterans. Iraq Star recruits plastic surgeons across the country to provide free cosmetic surgery for soldiers who want to fix their deformities including scars.

Scars To Freedom
Scars to Freedom Foundation, provides FREE scar revision to all Military Veterans. This is our way of thanking them for their sacrifice and service for our Country.